専門：
研究テーマ
(1) ヒト生殖補助医療(ART)のための総合支援装置の開発
(2) 受精卵の品質評価に関する研究
(3) 超音波を用いた非接触硬さ計測に関する研究
(4) 肝硬変、前立腺癌等の組織に見る臓器硬化のメカニズムに関する研究
(5) 再生組織の培養法に関する研究
略歴
大阪教育大学教育学部附属高等学校天王寺校舎
大阪大学基礎工学部生物工学科
大阪大学大学院基礎工学研究科システム人間系専攻修了
博士（工学）（日本大学）
ルーレオ大学博士研究員兼任 2009-
担当科目：電気電子数学Ⅰ、電気回路Ⅰ,Ⅱ及び演習、情報リテラシ入門、基礎プログラミング及び演習、電気工学実験Ⅱ,Ⅲ
研究室：
次世代工学技術センター(NEWCAT), 2F
医療工学第一研究室
tel：024-956-8926
fax：024-956-8948
e-mail：murayama@ee.ce.nihon-u.ac.jp
Murayama's Home Page: http://www.ee.ce.nihon-u.ac.jp/~murayama/top.htm
Book Chapters:
Shigeo Saito, Ken Sawai, Yoshinobu Murayama, Keiichi Fukuda, and Kazunari Yokoyama
“Nuclear Transfer of Animal ES Cells to Study Nuclear Reprogramming of Human Stem Cells”
in Neural Stem Cells Methods and Protocols, 2nd edition
Methods in Molecular Biology, NJ, Humana Press, 2008;438:151-69.
尾股定夫、村山嘉延
"触診を定量化する触覚センサの開発"、in 超五感センサの開発最前線、Tokyo、nts、2005、pp.321-340
Papers:
水野仁二、乾裕昭、中村寛子、赤石一幸、安齋憲、菊池瑛子、渡邉百合、野口香里、村山嘉延
ARTのための低毒性・完全無血清ガラス化保存システムの開発：クライオナノホールガラス化コンテナを用いたガラス化保存
日本受精着床学会雑誌、26(1):32-40, 2009
Fukaya et al.
Improvement of Hydrogelation Abilities and Handling of Photocurable Gelatin-based Cross-linking Materials
Journal of Biomedical Materials Research, 2009, in press
Tomonori Oie, Yoshinobu Murayama, Toru Fukuda, Chiharu Nagai, Sadao Omata, Keiichi Kanda, Hitoshi Yaku, Yasuhide Nakayama
Local elasticity imaging of vascular tissues by tactile mapping syste
Journal of Artificial Organs,vol.12, pp.40-46, 2009
C Fukaya, A Ishikawa, Y Nakayama, Y Murayama, S Omata, Y Hosaka, T Nakagawa
Development of a Photocurable Gelatin-based Gelation Material for Application to Periodontal Regeneration
Journal of Photochemistry and Photobiology A: Chemistry, vol.199, Issues 2-3, pp.255-260, 2008
Yoshinobu Murayama, Mitsutoshi Yoshida, Jinji Mizuno, Hiroko Nakamura, Sumiko Inoue, Yuri Watanabe, Kazuyuki Akaishi, Hiroaki Inui, Chirstos E. Constantinou and Sadao Omata
Elasticity Measurement of Zona Pellucida Using a Micro Tactile Sensor to Evaluate Embryo Quality.
Journal of Mammalian Ova Research, Journal of Mammalian Ova Research, vol.25, No.1, pp.8-16, 2008
乾裕昭、赤石一幸、中村寛子、水野仁二、村山嘉延、渡辺奈津美、吉田涼、渡辺明彦、安齋憲、尾股定夫
マイクロタクタイルセンサを用いたヒト卵の品質評価
日本受精着床学会雑誌、25(1):116-119, 2008
Yoshinobu Murayama, Mineyuki Haruta, Yuichi Hatakeyama, Takayuki Shiina, Hiroshi Sakuma, Seichi Takenoshita, Sadao Omata, and Christos E. Constantinou
Development of a New Instrument for examination of Stiffness in the Breast using Haptic Sensor Technology
Sensors and Actuators A, 143 (2008) 430-438
圧電セラミック素子を利用したRemote Haptic型カテーテルの開発に関する基礎的研究
春田峰雪、村山嘉延、尾股定夫
電気学会E部門論文誌、127:12(2007) 546-552
Olof Lindahl, Christos Constantinou, Anders Eklund, Yoshinobu Murayama, Per Hallberg and Sadao Omata
Review of Tactile Resonance Sensors in Medicine
Medical & Biological Engineering & Computing, in press
Yoshinobu Murayama, Jinji Mizuno, Hirokazu Kamakura, Yoichi Fueta, Hiroko Nakamura, Kazuyuki Akaishi, Ken Anzai, Akihiko Watanabe, Hiroaki Inui and Sadao Omata
Mouse Zona Pellucida Dynamically Changes its Elasticity during Oocyte Maturation, Fertilization and Early Embryo Development.
Human Cell, 19:4(2006)119-125
Yoshinobu Murayama, Christos E. Constantinou and Sadao Omata
Development of Tactile Mapping system suitable for the characterization of tissue engineering materials using novel tactile sensing technology
Sensors and Actuators A, 120:2(2005)543-549
Yoshinobu Murayama, Christos E. Constantinou and Sadao Omata
Remote Sensing of Mechanical Properties of Materials Using a Novel Ultrasound Transducer and Signal Processing
IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 52:3(2005)439-444
Yoshinobu Murayama and Sadao Omata
Considerations in design and sensitivity optimization of the Micro Tactile Sensor
IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 52:3(2005)434-438
Sadao Omata, Yoshinobu Murayama and Christos E. Constantinou
Real Time Robotic Tactile Sensor System for the Determination of the Physical Properties of Biomaterials
Sensors and Actuators A, 112:2-3(2004)278-285
Yoshinobu Murayama, Christos E. Constantinou and Sadao Omata
Fabrication of Micro Tactile Sensor for the measurement of micro scale local elasticity
Sensors and Actuators A, 109:3(2004)202-207
Yoshinobu Murayama, Christos E. Constantinou and Sadao Omata
Micro-mechanical sensing platform for the characterization of the elastic properties of the ovum via uniaxial measurment
Journal of Biomechanics, 37:1(2004)67-72
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Itoi F, Himaki T, Kubota C, Hirose J, Miyamura M, Hamano S, Murayama Y, Omata S, Yoshida M
Differences exist in zona pellucida hardness between in vivo- and in vitro-generated bovine embryos
Source: REPRODUCTION FERTILITY AND DEVELOPMENT 19 (1): 207-207 181 2007
Akimasa Nojiri, Yoshinobu Murayama, Sadao Omata
Fundamental investigation into sensitivity factor of resonance sensor using phase shift method
Proceedings of the 23rd Sensor Symposium, 2006, pp.266-269
Masaaki Ichikawa, Yoshinobu Murayama, Sadao Omata
Development of new magnetic sensor system using the phase shift method.
Proceedings of the 23rd Sensor Symposium, 2006, pp.300-303
Yasuyoshi Nakatsugawa, Yoshinobu Murayama, Sadao Omata
Development of new optical system using phase shift circuit and its applications.
Proceedings of the 23rd Sensor Symposium, 2006, pp.312-315
Mineyuki Haruta, Yoshinobu Murayama, Sadao Omata
Development of new ultrasound catheter for measurement the stiffness of tumor in blood vessel
Proceedings of the 23rd Sensor Symposium, 2006, pp.412-415
表層顆粒の放出は透明帯反応にとって十分条件であるか?
村山嘉延, 笛田洋一, 鎌倉大和, 中村寛子, 水野仁二, 赤石一幸, 乾裕昭, 尾股定夫
Journal of Mammalian ova Research, 23(2) : 135, 2006.
ヒト生殖補助医療技術(ART)のための卵子評価システムの開発-有効性と安全性の検証-
赤石一幸, 中村寛子, 水野仁二, 笛田洋一, 鎌倉大和, 村山嘉延, 尾股定夫, 渡辺奈津美, 平山和宏, 栗城瑛子, 渡辺明彦, 乾裕昭
Journal of Mammalian ova Research, 23(2) : 144, 2006.
ヒト生殖補助医療技術(ART)のための新しいストレッチ共培養システム-共培養システムへの機械的ストレスの有効性の検証-
水野仁二, 中村寛子, 成瀬恵治, 石田敬雄, 村山嘉延, 尾股定夫, 赤石一幸, 渡辺奈津美, 平山和宏, 栗城瑛子, 渡辺明彦, 乾裕昭
Journal of Mammalian ova Research, 23(2) : 146, 2006.
Takayuki Shiina, Yoshinobu Murayama, Yoichi Hatakeyama, Seiichi Takenoshita, Sadao Omata
Development of a breast cancer checker using a tactile array sensor and a tactile display system
Proceedings of the 22nd Sensor Symposium, 2005, pp.402-405
Toshikuni Yajima, Tatsu Fukuda, Yoshinobu Murayama, Sadao Omata
Two-dimensional elasticity distribution measurement of sliced tissue
Proceedings of the 22nd Sensor Symposium, 2005, pp.412-415
村山嘉延、笛田洋一、中村寛子、水野仁二、赤石一幸、乾裕昭、尾股定夫
ヒト生殖補助医療技術（ＡＲＴ）のための卵子評価システムの開発－Ⅰ
－受精前後におけるマウス卵子透明帯の工学的弾性評価－
Journal of Mammalian Ova Research, Volume 22, No.2, pp.24, 2005
中村寛子、笛田洋一、水野仁二、村山嘉延、赤石一幸、乾裕昭、尾股定夫
ヒト生殖補助医療技術（ＡＲＴ）のための卵子評価システムの開発－Ⅱ
－マウス拡張期胚盤胞の工学的弾性評価－
Journal of Mammalian Ova Research, Volume 22, No.2, pp.25, 2005
Yoshinobu Murayama, Christos E. Constantinou, Sadao Omata, Yoichi Fueta, Jinji Mizuno ,Akaishi Kazuyuki and Hiraaki Inui
Estimation systemdevice for human Assisted Reproductive Technology (ART): Micro-mechanical sensing platform for the characterization of the elastic properties of the ovum via uniaxial measurement.
12th World Congress on Human Reproduction, (2005)521-523
Yoshinobu Murayama, Christos E. Constantinou, Sadao Omata
Functional Design of the Micro Tactile Sensor for Tactile Mapping of Sliced Thin Tissues
Proceedings of the IASTED International Conference on Biomedical Engineering, 2005, pp.197-200
Sadao Omata, Yoshinobu Murayama and Christos E. Constantinou
Multi-Sensory Surgical Support System incorporating Tactile, Visual and Auditory Perception Modalities
Studies in Health Technology and Informatics, 111(2005)369-371
Yoshinobu Murayama and Sadao Omata
Sensitivity Optimization of the Micro Tactile Sensor
Proceedings of the 21th Sensor Symposium, 2004, pp.301-304
Yoshinobu Murayama, Chris. E. Constantinou and Sadao Omata
Intuitive Micromanipulation with Haptic Audio Feedback
Proceedings of CIT2004 (IEEE Computer Society Press), pp.907-911
Chris. E. Constantinou, Sadao Omata and Yoshinobu Murayama
Multisensory surgical support system incorporating, tactile, visual and auditory perception modalities
Proceedings of CIT2004 (IEEE Computer Society Press), pp.870-874
Sadao Omata, Yoshinobu Murayama and Chris E. Constantinou
Development of a novel surgical support instrument and virtual system incorporating new tactile sensor technology
Studies in Health Technology and Informatics, 2004, 98: 288-290
Yoshinobu Murayama and Sadao Omata
Fabrication of Micro Tactile Sensor and Aplication for Measurement of Young's Modulus of Ovum
Proceeding of the 20th Sensor Symposium, 2003. pp.131-134
Sadao Omata, Yoshinobu Murayama, and Christos E. Constantinou
Dvelopment of breast cancer checker using new tactile sensors
Proceeding of the 20th Sensor Symposium, 2004, pp.431-435
Sadao Omata, Yoshinobu Murayama and Chris E.Constantinou
Development of a New Tactile Sensor for Application to Robotics
Proceeding of the 20th Sensor Symposium, 2003. pp.303-307
Sadao Omata, Yoshinobu Murayama and Chris E.Constantinou
Development of a New Scanning Micro-Biosensor System for the Measurement of Stiffness Suitable for the Characterization of Tissue Engineering Materials
Proceeding of the 20th Sensor Symposium, 2003. pp.185-189
Yoshida Mitsutoshi, Imura Hitomi, Murayama Yoshinobu, et al.
Use of a piezo-electric ceramic tactile sensor to evaluate zona pellucida hardness at different stages of pig oocyte and embryo generated in vitro.
BIOL REPROD 66: 518 Suppl. 1 2002
Komatsu H, Murayama Y, Iwaki T, Tsukamoto I, Ogli K, Oda Y
Effects of enflurane on the long-term potentiation in the hippocampus.
Progress in Anesthetic Mechanism 6: 515-518, 2000